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NDE1 (nudE nuclear distribution gene E homolog 1 (A. nidulans)) Blocking Peptide (100ug)

NDE1 (nudE nuclear distribution gene E homolog 1 (A. nidulans)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-NDE1 antibody (Catalogue #: ARP47932_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP47932
Size: 100 ug
Weight: 38kDa
Gene: 54820
Format: Lyophilized powder
Target: NDE1 is required for centrosome duplication and formation and function of the mitotic spindle. It is essential for the development of the cerebral cortex. NDE1 may regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex
Alternative names: FLJ20101; HOM-TES-87; NUDE; NUDE1
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