Presku: | AAP32479 |
Size: | 100 ug |
Weight: | 104kDa |
Gene: | 9611 |
Format: | Lyophilized powder |
Target: | NCOR1 mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. |