Home  >  Products  >  NARF (nuclear prelamin A recognition factor) Blocking Peptide (the middle region of NARF)(100ug)
NARF (nuclear prelamin A recognition factor) Blocking Peptide (the middle region of NARF)(100ug)

NARF (nuclear prelamin A recognition factor) Blocking Peptide (the middle region of NARF)(100ug)

Supplier: Aviva Systems Biology Incorporated
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
This is a synthetic peptide designed for use in combination with anti-NARF Antibody(ARP54491_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP54491
Size: 100ug
Weight: 45kDa
Gene: 26502
Format: Lyophilized powder
Target: Several proteins have been found to be prenylated and methylated at their carboxyl-terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein-protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A- and B-type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue of a carboxyl-terminal CaaX motif. This post-translationally modified cysteine residue is removed from prelamin A when it is endoproteolytically processed into mature lamin A. NARF binds to the prenylated prelamin A carboxyl-terminal tail domain. It may be a component of a prelamin A endoprotease complex. NARF is located in the nucleus, where it partially colocalizes with the nuclear lamina. It shares limited sequence similarity with iron-only bacterial hydrogenases.
Alternative names: DKFZp434G0420; FLJ10067; IOP2
See Full Product Listings >