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NANA E.Coli - Recombinant E.Coli N-Acetylneuraminate Lyase                                   (5ug)

NANA E.Coli - Recombinant E.Coli N-Acetylneuraminate Lyase (5ug)

Product Introduction: N-acetylneuraminate lyase (NanA) is a member of a family of lyases, specifically the oxo-acid-lyases, which cleave carbon-carbon bonds. NanA catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetyl-D-mannosamine. NanA is inhibited by reduction with NaBH4 in the presence of the substrate, which indicates that it belongs to the Schiff-base-forming Class I aldolases. NanA is strongly inhibited by Cu2+ ions, p-chloromercuribenzoate and N-bromosuccinimide, it is also inhibited competitively by the reaction product, pyruvate, and its structurally related compounds, dihydroxyacetone and DL-glyceraldehyde.
Product Description: NANA produced in E.Coli is a single, non-glycosylated polypeptide chain containing 317 amino acids (1-297 a.a.) and having a molecular mass of 34.7kDa. NANA is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

5ug

Format

Sterile Filtered clear solution.

Presku

OOPA00138

Alternative Names

N-acetylneuraminate lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; nanA; npl; b3225; JW3194.

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