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NALP10 Antibody (OAPB01172)

NALP10 Antibody (OAPB01172)

NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1beta, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1beta processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Presku

OAPB01172

Target

NLR family pyrin domain containing 10

Alternative Names

NALP10; NACHT; LRR and PYD domains-containing protein 10; NLRP10; NOD8; CLR11.1; PAN5; PYNOD

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