MYST1 (8C4C) Antibody

MYST1 (MYST histone acetyltransferase 1) belongs to the MYST family of histone acetyltransferases, is a transcriptional regulator. The MYST family includes MYST1, named for the founding members MOZ, yeast YBF2 and SAS2 and TIP60. All members of this family contain a MYST region of about 240 amino acids with a canonical acetyl-CoA-binding site and a C2HC-type zinc finger motif. Most MYST proteins also have a chromodomain involved in protein-protein interactions and targeting transcriptional regulators to chromatin. Although MOF is e, Xenopus/Amphibian,pressed in both males and females, it associates with the , Xenopus/Amphibian, chromosome only in males. MOF contains a zinc-finger domain that is used to contact the globular part of the nucleosome and histone H4. The carbo, Xenopus/Amphibian,y terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histones.