Presku: | AAP41350 |
Size: | 100 ug |
Weight: | 64kDa |
Gene: | 4436 |
Format: | Lyophilized powder |
Target: | MSH2 was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. |