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MRGPRX1 (MAS-related GPR, member X1 ) Blocking Peptide (the C terminal of MRGPRX1)(100ug)

MRGPRX1 (MAS-related GPR, member X1 ) Blocking Peptide (the C terminal of MRGPRX1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MRGPRX1 Antibody (ARP59925_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP59925
Size: 100ug
Weight: 36kDa
Gene: 259249
Format: Lyophilized powder
Target: MRGPRX1 is an orphan receptor. MRGPRX1 is probably involved in the function of nociceptive neurons. It may regulate nociceptor function and/or development, including the sensation or modulation of pain. MRGPRX1 is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. MRGPRX1 is activated by the antimalarial drug, chloroquine and may mediate chloroquine-induced itch, in an histamine-independent manner.
Alternative names: GPCR; MRGX1; SNSR4
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