Supplier:
Aviva Systems Biology IncorporatedMRE11A (MRE11 meiotic recombination 11 homolog A (S. cerevisiae)) Blocking Peptide (the middle region of MRE11A)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP56645
Target
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Weight
80kDa
Gene Id
4361
Alternative Names
ATLD; HNGS1; MRE11; MRE11B
SUPPLIER INFO
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