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MRE11A (MRE11 meiotic recombination 11 homolog A (S. cerevisiae)) Blocking Peptide (the middle region of MRE11A)(100ug)

MRE11A (MRE11 meiotic recombination 11 homolog A (S. cerevisiae)) Blocking Peptide (the middle region of MRE11A)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MRE11A Antibody(ARP56645_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP56645
Size: 100ug
Weight: 80kDa
Gene: 4361
Format: Lyophilized powder
Target: This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alternative names: ATLD; HNGS1; MRE11; MRE11B
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