MRE11A antibody - N-terminal region (ARP56644_P050)

This is a rabbit polyclonal antibody against MRE11A. It was validated on Western Blot by Aviva Systems Biology. At Aviva Systems Biology we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (info@avivasysbio.com).MRE11A,MRE11 meiotic recombination 11 homolog A (S. cerevisiae),ATLD; HNGS1; MRE11; MRE11B; MRE11A,double-strand break repair protein MRE11A,double-strand break repair protein MRE11A,AT-like disease,MRE11 homolog 1,MRE11 homolog A,endo/exonuclease Mre11,meiotic recombination 11 homolog 1,meiotic recombination 11 homolog A,DNA recombination and repair protein

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SPECIFICATIONS

Size

50ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Format

Lyophilized powder

Presku

ARP56644_P050

Target

This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

Weight

80kDa

Gene Id

4361

Alternative Names

ATLD; HNGS1; MRE11; MRE11B