Mouse Myosin-VI (MYO6) ELISA Kit

Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Myosin 6 is a reverse-direction motor protein that moves towards the minus-end of actin filaments. Has slow rate of actin-activated ADP release due to weak ATP binding. Functions in a variety of intracellular processes such as vesicular membrane trafficking and cell migration. Required for the structural integrity of the Golgi apparatus via the p53-dependent pro-survival pathway. Appears to be involved in a very early step of clathrin-mediated endocytosis in polarized epithelial cells. May act as a regulator of F-actin dynamics. May play a role in transporting DAB2 from the plasma membrane to specific cellular targets. Required for structural integrity of inner ear hair cells.

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SPECIFICATIONS

Catalog Number

KTE70864

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Accession

Q64331

Additional Info

Mouse Myosin-VI (MYO6) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse MYO6. No significant cross-reactivity or interference between Mouse MYO6 and analogues was observed.