Mouse Metastasis-suppressor KiSS-1 (KISS1) ELISA Kit

Kisspeptin is a G-protein coupled receptor ligand for GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. It is recently become clear that kisspeptin-GPR54 signaling has an important role in initiating GnRH secretion at puberty, the extent of which is an area of ongoing research.Kisspeptin is a metastasis suppressor of melanomas and breast cancers without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms.

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SPECIFICATIONS

Catalog Number

KTE71212

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

280287

Accession

Q6Y4S4

Additional Info

Mouse Metastasis-suppressor KiSS-1 (KISS1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse KISS1. No significant cross-reactivity or interference between Mouse KISS1 and analogues was observed.