Mouse Doublesex- and mab-3-related transcription factor 1 (DMRT1) ELISA Kit

DMRT1 is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain). The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes, and is found to be the key sex-determining factor in chickens. This gene exhibits a gonad-specific and sexually dimorphic expression pattern, just like the related doublesex gene in fruit flies. The protein contains a nuclear localization signal between the 2 zinc-binding sites of the DM domain, which is located in the N terminus. Immunohistochemical analysis of adult human testis revealed that DMRT1 localized to nuclei of Sertoli cells, spermatogonia, and spermatocytes.

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SPECIFICATIONS

Catalog Number

KTE71242

Size

48T, 96T, 96T*5, 96T*50

Applications

ELISA

Reactivities

Mouse

Gene Id

50796

Accession

Q9QZ59

Additional Info

Mouse Doublesex- and mab-3-related transcription factor 1 (DMRT1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse DMRT1. No significant cross-reactivity or interference between Mouse DMRT1 and analogues was observed.