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Mouse Anti- Mouse Ly- 49F- PE(0.1 mg)

Mouse Anti- Mouse Ly- 49F- PE(0.1 mg)

The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors.1 Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated.2 These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains ~ 11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice.1

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SPECIFICATIONS

Size

0.1 mg

Hosts

Mouse

Clone

HBF- 719

Format

R- phycoerythrin (R- PE) Conjugate

Presku

OASB00600

Isotype

IgG1

SUPPLIER INFO

Aviva Systems Biology Incorporated

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