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Mouse Anti- Human SMAC/DIABLO- UNLB(0.1 mg)

Mouse Anti- Human SMAC/DIABLO- UNLB(0.1 mg)

SMAC/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. SMAC/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor of apoptosis protein (IAP) family, a major group of apoptosis regulators that have been shown to directly block caspase activity thereby blocking apoptosis. 1-6

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SPECIFICATIONS

Size

0.1 mg

Hosts

Mouse

Clone

2D12

Format

Purified (UNLB) Antibody

Presku

OASB01319

Isotype

IgG2b

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