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Mouse Anti- Human GSK- 3b- UNLB(0.1 mg)

Mouse Anti- Human GSK- 3b- UNLB(0.1 mg)

Glycogen synthase kinase-3 (GSK-3) is a protein serine kinase that phosphorylates glycogen synthase and thereby inactivates it. Insulin stimulates the dephosphorylation of glycogen synthase at the sites phosphorylated by GSK-3 and subsequently inhibits GSK-3 acutely leading to the stimulation of glycogen synthesis. GSK-3 signaling is performed by two isoforms, GSK-3alpha and GSK-3beta. The two isoforms share 97% sequence similarity within their catalytic domains. GSK-3 has also been shown to play a role in protein synthesis, cell adhesion, cell proliferation, cell differentiation, microtubule dynamics and cell motility.

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SPECIFICATIONS

Size

0.1 mg

Hosts

Mouse

Clone

3A11

Format

Purified (UNLB) Antibody

Presku

OASB01295

Isotype

IgG2a

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