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Mouse Anti- Human CD95/Fas- SPRD(100 tests)

Mouse Anti- Human CD95/Fas- SPRD(100 tests)

CD95, also known as Fas and Apo-1, is a 40-50 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. Crosslinking of CD95 by the monoclonal antibodies DX2 and DX3 delivers an apoptotic signal to Fas-sensitive cells, indicating that these monoclonal antibodies recognize a functional epitope of CD95.1-5

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SPECIFICATIONS

Size

100 tests

Applications

FC

Hosts

Mouse

Clone

DX- 3

Format

SpectralRed (SPRD) Conjugate

Presku

OASB01153

Isotype

IgG1

SUPPLIER INFO

Aviva Systems Biology Incorporated

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