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Morphine ((5 alpha 6 alpha) 7 8 didehydro-4 5 epoxy-17methylmorphinan-3 5diol) Antibody (Clone #: 3A6)(200ug)

Morphine ((5 alpha 6 alpha) 7 8 didehydro-4 5 epoxy-17methylmorphinan-3 5diol) Antibody (Clone #: 3A6)(200ug)

This is a mouse monoclonal antibody generated by using BSA-morphine conjugate. It was tested on ELISA.

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SPECIFICATIONS

Size

100ug

Applications

ELISA, ICC, IHC, IP

Hosts

Mouse

Format

Lyophilized powder

Presku

AMM00033

Target

Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.

Isotype

Mouse IgG

Alternative Names

Anti-Morphine antibody (3A6)

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