Morf4l1 (mortality factor 4 like 1 ) Blocking Peptide (the middle region of Morf4l1)(100ug)

This is a synthetic peptide designed for use in combination with anti-Morf4l1 Antibody (ARP47607_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100ug

Reactivities

Mouse

Format

Lyophilized powder

Presku

AAP47607

Target

Morf4l1 is a component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.

Weight

41kDa

Gene Id

The peptide is characterized by mass spectroscopy

Alternative Names

KIAA4002; MGC102415; MGC103105; MGC118047; MORFRG15; MRG15; TEG-189; Tex189; mKIAA4002