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MMS21 Antibody (OAPB01107)

MMS21 Antibody (OAPB01107)

MMS21, also known as NSE2, is a SUMO ligase that in combination with the SMC5/6 complex is required for the prevention of DNA damage induced apoptosis by facilitating DNA repair in human cells. MMS21-dependent sumoylation is integral and important to the cohesion mechanism and mitotic progression; this function appears to be independent of SMC6. MMS21 mediates SUMO attachment to various proteins such as SMC6L1 and TRAX, and possibly the cohesin components RAD21 and STAG2.

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB01107

Target

E3 SUMO-protein ligase NSE2

Alternative Names

MMS21; E3 SUMO-protein ligase NSE2; Non-SMC element 2; NSMCE2; MMS21 homolog

SUPPLIER INFO

Aviva Systems Biology Incorporated

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