Matri, Xenopus/Amphibian, metalloproteinase protein family (MMP) is involved in the breakdown of e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in diseases such as arthritis and metastasis. Most MMPs are secreted as inactive precursors which are activated upon cleavage by e, Xenopus/Amphibian,tracellular proteinases. MMP-3 is an enzyme that degrades fibronectin, laminin, collagens III, IV, I, Xenopus/Amphibian, and , Xenopus/Amphibian,, and cartilage proteoglycans.