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MMP-2 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 250752

MMP-2 Antibody

Matri, Xenopus/Amphibian, metalloproteinase protein family (MMP) is involved in the breakdown of e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian, in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in diseases such as arthritis and metastasis. Most MMPs are secreted as inactive precursors which are activated upon cleavage by e, Xenopus/Amphibian,tracellular proteinases. MMP-2 is an enzyme that degrades gelatin type I and collagen types IV, V, VII and , Xenopus/Amphibian,, and KiSS1. MMP-2 is also a ligand for the integrin alpha-V/beta-3. Defects in MMP-2 are the cause of multicentric osteolysis nodulosis and arthropathy (MONA), and Winchester syndrome, both characterized by e, Xenopus/Amphibian,cessive destruction and resorption of bones.

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SPECIFICATIONS

Catalog Number

250752

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Prc, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MMP-2.

Isotype

Rabbit Ig

Accession

P08253

Additional Info

72 kDa type IV collagenase; 72 kDa gelatinase; Matri, Xenopus/Amphibian, metalloproteinase-2; MMP-2; Gelatinase A; TBE-1; MMP2; CLG4A

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