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MLF1 (myeloid leukemia factor 1) Blocking Peptide (100ug)

MLF1 (myeloid leukemia factor 1) Blocking Peptide (100ug)

This is a synthetic peptide designed for use in combination with anti-MLF1 antibody (Catalogue #: ARP53757_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100 ug

Format

Lyophilized powder

Presku

AAP53757

Target

MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. It interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. MLF1 suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest.It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Weight

29kDa

Gene Id

4291

SUPPLIER INFO

Aviva Systems Biology Incorporated

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