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MIER1 (mesoderm induction early response 1 homolog (Xenopus laevis)) Blocking Peptide (100ug)

MIER1 (mesoderm induction early response 1 homolog (Xenopus laevis)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MIER1 antibody (Catalogue #: ARP34468_T100) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP34468
Size: 100 ug
Weight: 49kDa
Gene: 57708
Format: Lyophilized powder
Target: The association of hMI-ER1 with Sp1 represents a novel mechanism for the negative regulation of Sp1 target promoters. Results demonstrate that alternate use of a facultative intron regulates the subcellular localization of hMI-ER1 proteins and this may have important implications for hMI-ER1 function in the regulation of transcription. Repressor activity is due to interaction and recruitment of a trichostatin A-sensitive histone deacetylase 1 (HDAC1).
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