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MIC-1 Recombinant Protein (0.005 mg)

MIC-1 Recombinant Protein (0.005 mg)

GDF-15 belongs to the TGF-beta cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Human GDF-15/MIC-1 is a disulfide linked homodimeric protein consisting of two 114 amino-acid polypeptide chains.

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SPECIFICATIONS

Size

0.005 mg

Presku

OPPB00126

Alternative Names

MIC-1; Placental TGF(B); Prostate differentiation factor

SUPPLIER INFO

Aviva Systems Biology Incorporated

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