MHC Class I (HI21) Antibody

MHC Class I (HI21) antibody recognizes class I major histocompatibility comple, Xenopus/Amphibian, (or human leukocyte antigen) monomorphic antigen which is e, Xenopus/Amphibian,pressed widely on human nucleated cells such as lymphocytes,Mouse,onocytes/ macrophages, dendritic cells and other hematopoietic and non-hematopoietic nucleated cells, and platelets. The e, Xenopus/Amphibian,pression of HLA-I antigen varies with cell types and decreases with cell maturation, e.g. low e, Xenopus/Amphibian,pression on mature granulocytes and almost null on mature erythrocytes. HLA-I antigen is also e, Xenopus/Amphibian,pressed on most cells of human leukemic cell lines, but not or low in Daudi and K562 cell lines and nerve cells. In addition to membrane HLA-I antigen, a soluble form of HLA-I can be detected in serum.