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MGMT (O-6-methylguanine-DNA methyltransferase) Blocking Peptide (the middle region of MGMT)(100ug)

MGMT (O-6-methylguanine-DNA methyltransferase) Blocking Peptide (the middle region of MGMT)(100ug)


Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MGMT Antibody(ARP42038_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP42038
Size: 100ug
Weight: 22kDa
Gene: 4255
Format: Lyophilized powder
Target: MGMT is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA.MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.