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MGMT Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251378

MGMT Antibody

Methylated-DNA--protein-cysteine methyltransferase (MGMT) is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.

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SPECIFICATIONS

Catalog Number

251378

Size

0.1 mg

Applications

IHC

Reactivities

Hum, Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MGMT.

Isotype

Rabbit Ig

Accession

P16455

Additional Info

MGMT; O-6-methylguanine-DNA alkyltransferase; Methylated-DNA-protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase

SUPPLIER INFO

ABBIOTEC

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