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MGMT Antibody

MGMT Antibody

Cat no: 251378

Supplier: ABBIOTEC
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Methylated-DNA--protein-cysteine methyltransferase (MGMT) is involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. MGMT repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
Catalogue number: 251378
Reactivities: Human, Mouse, Rabbit
Applications: Immunohistochemistry
Size: 0.1 mg
Accession: P16455
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human MGMT.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Additional info: MGMT; O-6-methylguanine-DNA alkyltransferase; Methylated-DNA-protein-cysteine methyltransferase; 6-O-methylguanine-DNA methyltransferase
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