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mGluR5/1 Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 253172

mGluR5/1 Antibody

The metabotropic glutamate receptors (mGluRs) are key receptors in the modulation of e, Xenopus/Amphibian,citatory synaptic transmission in the central nervous system. They are implicated in many forms of neural plasticity as well as learning and memory and drug abuse. Group I metabotropic glutamate receptors (consisting of mGluR1 and mGluR5) are G-protein-coupled neurotransmitter receptors that are localized in the perisynaptic region of the postsynaptic membrane. When activated, Group I mGluRs lead to stimulation of phospholipase and activation of Protein Kinase C. The mGluR5 receptor appears to be essential for late phase LTP in area CA1 of the hippocampus.

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SPECIFICATIONS

Catalog Number

253172

Size

0.1 ml

Applications

IHC

Reactivities

Mouse, Rabbit

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of HEPES (pH7.5), 0.01% BSA, with 50% glycerol. Antibody was purified by immunogen affinity chromatography.

P Type

Rabbit Polyclonal Antibody

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of rat mGluR5/1.

Isotype

Rabbit Ig

Accession

P31424

Additional Info

Metabotropic glutamate receptor 5; mGluR5; m5; Gprc1e; Mglur5

SUPPLIER INFO

ABBIOTEC

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