Presku: | AAP36921 |
Size: | 100 ug |
Weight: | 41kDa |
Gene: | 17293 |
Format: | Lyophilized powder |
Target: | Somite boundaries formed during embryogenesis, at the interface between Notch1-activated and -repressed domains. Genetic and biochemical studies indicate that this interface is generated by suppression of Notch activity by mesoderm posterior 2 (Mesp2) through induction of the lunatic fringe gene (Lfng). It is proposed that the oscillation of Notch activity is arrested and translated in the wavefront by Mesp2. |