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MEK1 (Thr386) Antibody

MEK1 (Thr386) Antibody

Cat no: 252556

Supplier: ABBIOTEC
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MEK1 (MAPKK1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEKI (MAPKK1) activates ERK1 and ERK2 MAP kinases, enzymes which are involved in numerous signal transduction pathways. Defects in MEK1 (MAPKK1) are a cause of cardiofaciocutaneous syndrome (CFC syndrome), also known as cardio-facio-cutaneous syndrome. CFC syndrome is characterized by a distinctive facial appearance, heart defects and mental retardation. The sites on MEK 1 that are phosphorylated by MAP kinase are Thr292 and Thr386.
Catalogue number: 252556
Reactivities: Human, Mouse, Bovine, Chicken/Bird, Rabbit, Xenopus/Amphibian
Applications: Western Blot
Size: 0.1 ml
Accession: Q02750
Antigen: KLH-conjugated synthetic phosphopeptide encompassing a sequence surrounding Thr386 of human MEK1.
Format: Each vial contains 0.1 ml IgG in HEPES pH7.5, 150 mM NaCl, 0.01% BSA and 50% glycerol. Antibody was purified by immunogen affinity chromatography.
P type: Rabbit Polyclonal Antibody,Porcinehosphospecific Antibody
Isotype: Rabbit IgG
Additional info: MAPKK1; Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK1; MAP2K1; PRKMK2
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