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MEF2D (Human) cDNA (1ug)

MEF2D (Human) cDNA (1ug)

Supplier: Aviva Systems Biology Incorporated
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The ORF of human MEF2D is amplified by PCR using a high fidelity enzyme and sub-cloned into a Prokaryotic expression vector under the control of the tac promoter. The expression of the gene has been confirmed by Western blot using an anti-MEF2D polyclonal antibody.
Presku: ANA10200
Size: 1ug
Gene: 4209
Target: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific, growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. Plays a critical role in the regulation of neuronal apoptosis.
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