Reactivities: | Human |
Presku: | AAP58139 |
Size: | 100ug |
Weight: | 160kDa |
Gene: | 9282 |
Format: | Lyophilized powder |
Target: | The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein contains a bipartite nuclear localization signal. This gene is known to escape chromosome X-inactivation. |
Alternative names: | CRSP150; CRSP2; CSRP; CXorf4; DRIP150; EXLM1; MGC104513; RGR1; TRAP170 |