Supplier:
Aviva Systems Biology IncorporatedMDS1 antibody - N-terminal region (ARP38536_T100)
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SPECIFICATIONS
Size
100ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse
Format
Lyophilized powder
Presku
ARP38536_T100
Target
MDS1 is located at 3q26 170-400 kb upstream (telomeric) of EVI1 in the chromosomal region in which some of the breakpoints 5' of EVI1 have been mapped. MDS1 has been identified as a single gene as well as a previously unreported exon(s) of EVI1. MDS1 exists in normal tissues both as a unique transcript and as a normal fusion transcript with EVI1, with an additional 188 codons at the 5' end of the previously reported EVI1 open reading frame. In cells with translocation t (3;21), additional fusion transcripts are AML1-MDS1 and AML1-MDS1-EVI1. EVI1 and MDS1 are involved in leukemia associated with chromosomal translocation breakpoints in the region between these genes.
Weight
19kDa
Gene Id
4197
Alternative Names
PRDM3; MDS1-EVI1
SUPPLIER INFO
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