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MDR Antibody
ABBIOTEC

Supplier:

ABBIOTEC

Cat no: 251767

MDR Antibody

Multidrug resistance protein 1 (MDR) is a membrane-associated protein belonging to the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across e, Xenopus/Amphibian,tra- and intra-cellular membranes. MDR is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. MDR is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. MDR also functions as a transporter in the blood-brain barrier.

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SPECIFICATIONS

Catalog Number

251767

Size

0.1 mg

Applications

ICC, IHC

Reactivities

Hum

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

P Type

Mouse Monoclonal Antibody

Antigen

A mi, Xenopus/Amphibian,ture of human and hamster drug-resistant whole cells and crude plasma membranes.

Isotype

Mouse IgG1

Accession

Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD243; ABCB1; MDR1; PGY1

Clonality

PG-13

Additional Info

P08183

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