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MDC1 (mediator of DNA-damage checkpoint 1) Blocking Peptide (the C terminal of MDC1)(100ug)

MDC1 (mediator of DNA-damage checkpoint 1) Blocking Peptide (the C terminal of MDC1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MDC1 Antibody, made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP36798
Size: 100ug
Weight: 227kDa
Gene: 9656
Format: Lyophilized powder
Target: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
Alternative names: DKFZp781A0122; KIAA0170; MGC166888; NFBD1
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