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MCP 5 Mouse - Recombinant Mouse Monocyte Chemotactic Protein-5 (CCL12)

MCP 5 Mouse - Recombinant Mouse Monocyte Chemotactic Protein-5 (CCL12)

Product Introduction: MCP-5 (CCL12) is a cloned mouse CC chemokine most closely related to human MCP1 (66% amino acid sequence identity in the mature protein). MCP5 is expressed constitutively in the thymus and the lymph nodes. Under inflammatory conditions, moreover CCL12 expression is induced in activated macrophages and mast cells. The mouse MCP1 gene is mapped to the CC chemokine cluster on chromosome 11. Recombinant CCL12 is a potent chemoattractant for monocytes and lymphocytes but not neutrophils. At high concentrations, MCP-5 also chemoattracts eosinophils. CCL12 is a functional ligand for CCR2.
Product Description: MCP-5 Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 82 amino acids and having a molecular mass of 9.3kDa. The MCP5 is purified by proprietary chromatographic techniques.

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SPECIFICATIONS

Size

5ug

Format

Sterile Filtered White lyophilized (freeze-dried) powder.

Presku

OOPA00016

Alternative Names

C-C motif chemokine 12; MCP-1-related chemokine; Monocyte chemoattractant protein 5; Monocyte chemotactic protein 5; MCP-5; Small-inducible cytokine A12; Ccl12; Mcp5; Scya12.

SUPPLIER INFO

Aviva Systems Biology Incorporated

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