Reactivities: | Human |
Presku: | AAP63649 |
Size: | 100ug |
Weight: | 33kDa |
Gene: | 4158 |
Format: | Lyophilized powder |
Target: | MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. |
Alternative names: | ACTHR; MGC125798 |