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MBNL2 (muscleblind-like 2 (Drosophila)) Blocking Peptide (100ug)

MBNL2 (muscleblind-like 2 (Drosophila)) Blocking Peptide (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MBNL2 antibody (Catalogue #: ARP51632_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP51632
Size: 100 ug
Weight: 28kDa
Gene: 10150
Format: Lyophilized powder
Target: MBNL2 is a C3H-type zinc finger protein, which is similar to the Drosophila melanogaster muscleblind B protein.MBNL2 is a RNA-binding protein that binds to 5'ACACCC-3' core sequence. It binds to CUG triplet repeat expansion in myotonic dystrophy muscle cells by sequestering the target RNAs. MBNL2 seems to regulate expression and localization of ITGA3 by transporting it from the nucleus to cytoplasm. It may play a role in myotonic dystrophy pathophysiology (DM).
Alternative names: DKFZp781H1296; MBLL; MBLL39; MGC120625; MGC120626; MGC120628; PRO2032
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