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MBD1 (methyl-CpG binding domain protein 1 ) Blocking Peptide (the C terminal of MBD1)(100ug)

MBD1 (methyl-CpG binding domain protein 1 ) Blocking Peptide (the C terminal of MBD1)(100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MBD1 Antibody (ARP32693_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Reactivities: Human
Presku: AAP32693
Size: 100ug
Weight: 69kDa
Gene: The peptide is characterized by mass spectroscopy
Format: Lyophilized powder
Target: The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alternative names: CXXC3; PCM1; RFT
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