Supplier:
Aviva Systems Biology IncorporatedMAT1A antibody - C-terminal region (ARP41399_T100)
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SPECIFICATIONS
Size
100ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum, Mouse, Rat, Bov, Can, Ch/Bird, Prc, ZF/Fish
Format
Lyophilized powder
Presku
ARP41399_T100
Target
MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. S-adenosylmethionine is the source of methyl groups for most biological methylations. MAT1A is found as a homotetramer (MAT I) or a homodimer (MAT III) whereas a third form, MAT II (gamma), is encoded by the MAT2A gene. Mutations in its gene are associated with methionine adenosyltransferase deficiency.This gne encodes methionine adenosyltransferase I (alpha isoform), which catalyzes the formation of S-adenosylmethionine from methionine and ATP. Methionine adenosyltransferase deficiency is caused by recessive and dominant mutations, the latter identified in autosomal dominant persistant hypermethioninemia.
Weight
44kDa
Gene Id
4143
Alternative Names
MAT; MATA1; SAMS; SAMS1
SUPPLIER INFO
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