MASP1 (mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) ) Blocking Peptide (the N terminal of MASP1)(100ug)

Supplier: Aviva Systems Biology Incorporated

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Description
Additional Information

This is a synthetic peptide designed for use in combination with anti-MASP1 Antibody (ARP63877_P050), made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

Reactivities:	Human
Presku:	AAP63877
Size:	100ug
Weight:	28kDa
Gene:	5648
Format:	Lyophilized powder
Target:	This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway.
Alternative names:	CRARF; CRARF1; DKFZp686I01199; FLJ26383; MASP; MGC126283; MGC126284; PRSS5; RaRF