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MARCH8 (membrane-associated ring finger (C3HC4) 8) Blocking Peptide (the middle region of protein) (100ug)

MARCH8 (membrane-associated ring finger (C3HC4) 8) Blocking Peptide (the middle region of protein) (100ug)

This is a synthetic peptide designed for use in combination with anti-MARCH8 antibody (Catalogue #: ARP43401_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.

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SPECIFICATIONS

Size

100 ug

Format

Lyophilized powder

Presku

AAP43401

Target

MARCH8 is an E3 ubiquitin-protein ligase that may regulate immune responses by promoting ubiquitination of MHC-II and CD86, which leads to their subsequent endocytosis and lysosomal degradation. It may also promote ubiquitination and endocytosis of TFRC and FAS. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.

Weight

33kDa

Gene Id

220972

Alternative Names

MARCH-VIII; MIR; RNF178; c-MIR

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