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MARCH4 (membrane-associated ring finger (C3HC4) 4) Blocking Peptide (the N terminal of protein) (100ug)

MARCH4 (membrane-associated ring finger (C3HC4) 4) Blocking Peptide (the N terminal of protein) (100ug)

Supplier: Aviva Systems Biology Incorporated
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This is a synthetic peptide designed for use in combination with anti-MARCH4 antibody (Catalogue #: ARP43280_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
Presku: AAP43280
Size: 100 ug
Weight: 45kDa
Gene: 57574
Format: Lyophilized powder
Target: MARCH4 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of MHC-I and CD4, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Alternative names: MARCH-IV; MGC104908; RNF174
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