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MAP4K4 (3C7B) Antibody

MAP4K4 (3C7B) Antibody

Cat no: 252792


Supplier: ABBIOTEC
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MAP4K4 (Mitogen-activated protein kinase kinase kinase kinase 4) is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1,Mouse,AP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway.
Catalogue number: 252792
Reactivities: Human
Applications: Western Blot
Size: 0.1 ml
Accession: O95819
Antigen: Purified recombinant fragment of MAP4K4(aa400-500) e, Xenopus/Amphibian,pressed in E. coli.
Format: Each vial contains 0.1 ml ascitic fluid with 0.03% sodium azide.
P type: Mouse Monoclonal Antibody
Isotype: Mouse IgG1
Clonality: 3C7B5
Additional info: Mitogen-activated protein kinase kinase kinase kinase 4; HPK/GCK-like kinase HGK; MAPK/ERK kinase kinase kinase 4; MEK kinase kinase 4; MEKKK 4; Nck-interacting kinase HGK; KIAA0687; NIK MAP4K4