Reactivities: | Human |
Presku: | AAP60314 |
Size: | 100ug |
Weight: | 121kDa |
Gene: | 4134 |
Format: | Lyophilized powder |
Target: | MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. |
Alternative names: | DKFZp779A1753; MGC8617 |