Reactivities: | Human |
Presku: | AAP42161 |
Size: | 100ug |
Weight: | 104kDa |
Gene: | 9020 |
Format: | Lyophilized powder |
Target: | This gene encodes mitogen-activated protein kinase kinase kinase 14, which is a serine/threonine protein-kinase. This kinase binds to TRAF2 and stimulates NF-kappaB activity. It shares sequence similarity with several other MAPKK kinases. It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. |
Alternative names: | FTDCR1B; HS; HSNIK; NIK |