Supplier:
Aviva Systems Biology IncorporatedMANF (mesencephalic astrocyte-derived neurotrophic factor) Blocking Peptide (the C terminal of MANF)(100ug)
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SPECIFICATIONS
Size
100ug
Reactivities
Hum
Format
Lyophilized powder
Presku
AAP59608
Target
MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of MANF gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Weight
21kDa
Gene Id
7873
Alternative Names
ARMET; ARP; MGC142148; MGC142150
SUPPLIER INFO
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