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MANF Antibody (OAPB00580)

MANF Antibody (OAPB00580)

MANF, also known as ARMET, was initially identified as a protein containing an arginine-rich region that was highly mutated in a variety of tumors. More recently it was identified as a mesencephalic astrocyte-derived neurotrophic factor with selectivity for dopaminergic neurons, similar to glial cell line-derived neurotrophic factor (GDNF) and CDNF. In rat brain slices, MANF enhanced nigral gamma-aminobutyric acid release. Like GDNF and CDNF, MANF has selective neuroprotective activity for dopaminergic neurons suggesting that it may be indicated for the treatment of Parkinson

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SPECIFICATIONS

Size

0.1 mg

Applications

ELISA, IHC, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Presku

OAPB00580

Target

(CT) Mesencephalic astrocyte-derived neurotrophic factor

Alternative Names

MANF (CT); Mesencephalic astrocyte-derived neurotrophic factor; arginine-rich mutatedin early stage tumor; ARMET; ARP

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