Supplier:
Aviva Systems Biology IncorporatedMANF antibody - C-terminal region (ARP59608_P050)
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SPECIFICATIONS
Size
50ug
Applications
WB
Hosts
Rabbit
Reactivities
Hum
Format
Lyophilized powder
Presku
ARP59608_P050
Target
MANF is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of MANF gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Weight
21kDa
Gene Id
7873
Alternative Names
ARMET; ARP; MGC142148; MGC142150
SUPPLIER INFO
Applications
ELISA, WB
Hosts
Mouse
Applications
IHC
Hosts
Mouse
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